This is why the birth control shot for men is a great alternative for birth control for men. They can be forgotten or done the wrong way or be very permanent. However, these options aren’t always the best and sometimes not very effective as a birth control method. The options included female condoms, the Pill, and patches to name a few.įor men, the only real birth control options were the pullout method, vasectomies, and condoms. Now, there is a birth control shot that has been successful in decreasing a man’s sperm count and has had a success rate of 96%.īefore this new birth control shot for men was created, hormonal birth control was only exclusively for women. However, until just recently, birth control has been mostly for women. It can help with regulating periods, clearing up skin, and help with hormonal issues as well. "Male contraceptives will add to the method mix, providing new options that allow men and women to contribute in whatever way they deem appropriate to contraceptive use," argues the nonprofit Male Contraceptive Initiative, which engages in fundraising and advocacy.Male Birth Control Shot Is Now Available And It Works!įor the most part birth control has only been really exclusive to women with the exception of condoms.īirth Control is very important as it helps prevent pregnancy and it also can help prevent STDs depending on the type of birth control used.
"There is no guarantee that it will work.but I would really be surprised if we didn't see an effect in humans as well," she added.Ī persistent question about future male contraceptive pills has been whether women will trust men to use them.īut surveys have shown that most women would in fact have faith in their partners, and significant numbers of men have indicated they would be open to the medication. "I'm optimistic this will move forward quickly," she said, envisaging a possible timeline to market in five years or under. The team, which received funding from the National Institutes of Health and the Male Contraceptive Initiative, is working with a company called YourChoice Therapeutics to start human trials by the third or fourth quarter of 2022, said Georg. The researchers monitored weight, appetite, and overall activity, finding no apparent adverse impacts, although mice of course can't report side effects like headaches or mood changes.įour to six weeks after they were taken off the drug, the mice could once more sire pups. When administered orally to male mice for four weeks, YCT529 drastically reduced sperm counts and was 99 percent effective in preventing pregnancy in a mating trial. Their chemical, known as YCT529, was also designed to interact specifically with RAR-alpha, and not two other related receptors RAR-beta and RAR-gamma, in order to minimize potential side effects. "If we know what the keyhole looks like, then we can make a better key – that's where the computational model comes in," said Noman. They identified the best molecular structure with the help of a computer model. Retinoic acid needs to interact with RAR-alpha to perform these functions, and lab experiments have shown mice without the gene that creates RAR-alpha are sterile.įor their work, Noman and Georg developed a compound that blocks the action of RAR-alpha. Inside the body, vitamin A is converted into different forms, including retinoic acid, which plays important roles in cell growth, sperm formation, and embryo development. To develop a non-hormonal drug, Noman, who works in the lab of Professor Gunda Georg, targeted a protein called " retinoic acid receptor (RAR) alpha". The female pill also carries side effects, including blood-clotting risks – but since women face becoming pregnant in the absence of contraception, the risk calculation differs. The problem with this approach, however, was that it caused side effects such as weight gain, depression, and increased levels of a cholesterol known as low-density lipoprotein, which increases heart disease risks. The female pill uses hormones to disrupt the menstrual cycle, and historic efforts to develop a male equivalent targeted the male sex hormone testosterone. Vasectomy reversal surgery is expensive and not always successful. "Multiple studies showed that men are interested in sharing the responsibility of birth control with their partners," he said – but until now, there have been only two effective options available: condoms or vasectomies. The findings will be presented at the American Chemical Society's spring meeting, and mark a key step towards expanding birth control options – as well as responsibilities – for men.Įver since the female birth control pill was first approved in the 1960s, researchers have been interested in a male equivalent, Md Abdullah Al Noman, a graduate student at the University of Minnesota who will present the work, told AFP.
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